Antimicrobials

Reports on the emergence and prevalence of resistant bacterial infections in hospitals and communities raise concerns that we may soon no longer be able to rely on antibiotics as a way to control infectious diseases. Effective medical care would require the constant introduction of novel antibiotics to keep up in the “arms race” with resistant pathogens. This book closely examines the latest developments in the field of antibacterial research and development. It starts with an overview of the growing prevalence of resistant Gram-positive and Gram-negative pathogens, including their various resistance mechanisms, prevalence, risk factors and therapeutic options. The focus then shifts to a comprehensive description of all major chemical classes with antibacterial properties, their chemistry, mode of action, and the generation of analogs; information that provides the basis for the design of improved molecules to defeat microbial infections and combat the emerging resistances. In closing, recently developed compounds already in clinical use, those in preclinical or first clinical studies, and a number of promising targets to be exploited in the discovery stage are discussed.

A Medical book by Matthias Gotte,Albert Berghuis,Greg Matlashewski,Mark Wainberg,Donald Sheppard, with totalpages 700, file format PDF ePub, language English, file download 815 kb. While many volumes have been written about various aspects of antimicrobial resistance, this book is a comprehensive reference work. All manifestations of

A Science book by Rosaleen Anderson,Paul W. Groundwater,Adam Todd,Alan Worsley, with totalpages 376, file format PDF ePub, language English, file download 1422 kb. Antibacterial agents act against bacterial infection either bykilling the bacterium or by arresting its growth. They do this bytargeting bacterial DNA and

A Medical book by Thomas J. Dougherty,Michael J. Pucci, with totalpages 1127, file format PDF ePub, language English, file download 775 kb. This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group of highly experienced in

A Medical book by T. J. Franklin,G. A. Snow, with totalpages 166, file format PDF ePub, language English, file download 1176 kb. The subject is one of major interest in basic microbiology and infectious diseases and the book is a known classic.

A Medical book by Claudio O. Gualerzi,Letizia Brandi,Attilio Fabbretti,Cynthia L. Pon, with totalpages 576, file format PDF ePub, language English, file download 539 kb. Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their discov

A Science book by Richard G. Wax,Kim Lewis,Abigail A. Salyers,Harry Taber, with totalpages 448, file format PDF ePub, language English, file download 428 kb. The enormous genetic flexibility of bacteria jeopardizes the usefulness of currently available antibiotics, and requires new approaches to antibiotic disco

A Medical book by André Bryskier, with totalpages 1426, file format PDF ePub, language English, file download 1268 kb. Comprehensively covers the history, chemistry, synthesis, mechanisms of action, pharmacology, and efficacy of all antimicrobial agents. Serves as a referen

A Medical book by Ola Sköld, with totalpages 224, file format PDF ePub, language English, file download 1959 kb. This book, which is the translated version of a Swedish book, combines a general introduction of a variety of antibiotics with a more in-depth discussion o

A Medical book by Alexander A. Vinks,Hartmut Derendorf,Johan W. Mouton, with totalpages 466, file format PDF ePub, language English, file download 446 kb. Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharma

A Medical book by José-Luis Capelo-Martínez,Gilberto Igrejas, with totalpages 720, file format PDF ePub, language English, file download 1112 kb. This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into t

A Technology & Engineering book by Nicola Cioffi,Mahendra Rai, with totalpages 556, file format PDF ePub, language English, file download 1174 kb. There is a high demand for antimicrobials for the treatment of new and emerging microbial diseases. In particular, microbes developing multidrug resistance

A Science book by Patricia L. Keen,Mark H. M. M. Montforts, with totalpages 602, file format PDF ePub, language English, file download 1689 kb. Examines effects of the environmental distribution of antimicrobial resistance genes on human health and the ecosystem Resistance genes are everywhere in n

A Medical book by Guangshun Wang, with totalpages 290, file format PDF ePub, language English, file download 1878 kb. This book is a printed edition of the Special Issue "Identification and Characterization of Antimicrobial Peptides with Therapeutic Potential" that was pub

A Science book by Tomás G. Villa,Patricia Veiga-Crespo, with totalpages 316, file format PDF ePub, language English, file download 764 kb. Since penicillin and salvarsan were discovered, a number of new drugs to combat infectious diseases have been developed, but at the same time, the number o

A book by Ghassan M. Matar,Antoine Andremont, with totalpages N.A, file format PDF ePub, language English, file download 1568 kb.

A Medical book by Steeve Giguère,John F. Prescott,Patricia M. Dowling, with totalpages 704, file format PDF ePub, language English, file download 778 kb. The Fifth Edition of Antimicrobial Therapy in Veterinary Medicine, the most comprehensive reference available on veterinary antimicrobial drug use, has bee

A Science book by Céline Pulcini,Onder Ergonul,Füsun Can,Bojana Beović, with totalpages 394, file format PDF ePub, language English, file download 852 kb. Antimicrobial Stewardship (AMS), Volume Two includes the experience of ESGAP workshops and courses on antibiotic stewardship since 2012. It combines clinic

A Science book by Mrinal K. Bhattacharjee, with totalpages 219, file format PDF ePub, language English, file download 1538 kb. This textbook discusses how the various types of antibiotics and related drugs work to cure infections. Then it delves into the very serious matter of how

A Medical book by David L. Schlossberg,Rafik Samuel, with totalpages 480, file format PDF ePub, language English, file download 477 kb. A comprehensive compendium of all commonly used antibiotics, including indications, side effects, dosage information, and drug/food interactions Antibiotic

A Medical book by Antonella Piozzi,Iolanda Francolini, with totalpages 400, file format PDF ePub, language English, file download 1855 kb. The rapid increase in the emergence of antibiotic-resistant bacterial strains, combined with a dwindling rate of discovery of novel antibiotic molecules, h

A Science book by Aníbal de J. Sosa,Denis K. Byarugaba,Carlos F. Amábile-Cuevas,Po-Ren Hsueh,Samuel Kariuki,Iruka N. Okeke, with totalpages 554, file format PDF ePub, language English, file download 316 kb. Avoiding infection has always been expensive. Some human populations escaped tropical infections by migrating into cold climates but then had to procure fu

A book by Jun Lin,Kunihiko Nishino,Marilyn C. Roberts,Marcelo Tolmasky,Rustam I. Aminov,Lixin Zhang, with totalpages N.A, file format PDF ePub, language English, file download 1546 kb. Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of an

A Medical book by Douglas Mayers, with totalpages 692, file format PDF ePub, language English, file download 1601 kb. This ? rst edition of Antimicrobial Drug Resistance grew out of a desire by the editors and authors to have a comprehensive resource of information on anti

A Medical book by Luca Guardabassi,Lars Bogø Jensen,Hilde Kruse, with totalpages 240, file format PDF ePub, language English, file download 1398 kb. The first book to offer practical guidelines on the prudent andrational use of antimicrobials in animals. Drawing onmultidisciplinary expertise to offer in

A book by Ana Díez-Pascual, with totalpages N.A, file format PDF ePub, language English, file download 968 kb. Antibacterial Activity of Nanomaterials.

A Medical book by Institute of Medicine,Board on Global Health,Forum on Microbial Threats, with totalpages 496, file format PDF ePub, language English, file download 1524 kb. Years of using, misusing, and overusing antibiotics and other antimicrobial drugs has led to the emergence of multidrug-resistant 'superbugs.' The IOM's Fo

A Technology & Engineering book by Atul Tiwari, with totalpages 596, file format PDF ePub, language English, file download 1533 kb. Handbook of Antimicrobial Coatings is the first comprehensive work on the developments being made in the emerging field of antimicrobial coatings. Crucial

A Medical book by Marc Stadler,Petra Dersch, with totalpages 496, file format PDF ePub, language English, file download 417 kb. This volume focuses on antibiotics research, a field of topical significance for human health due to the worrying increase of nosocomial infections caused

A book by Etienne Giraud,Ivan Rychlik,Axel Cloeckaert, with totalpages N.A, file format PDF ePub, language English, file download 1790 kb. Multiple relationships exist between antimicrobial resistance and bacterial virulence, and the spread of clones combining multiple antibiotic resistance an

A Science book by Muhammad Zaffar Hashmi, with totalpages 456, file format PDF ePub, language English, file download 955 kb. This volume summarizes and updates information about antibiotics and antimicrobial resistance (AMR)/antibiotic resistant genes (ARG) production, including

A Medical book by Paul H. Axelsen, with totalpages 141, file format PDF ePub, language English, file download 991 kb. For many medical students and physicians, the task of quickly obtaining sufficient, accurate, and up-to-date information about the pharmacology of antimicr

A Technology & Engineering book by Jose Maria Lagaron,Maria Jose Ocio,Amparo Lopez-Rubio, with totalpages 608, file format PDF ePub, language English, file download 1541 kb. The pioneering guide on the design, processing, and testingof antimicrobial plastic materials and coatings The manifestation of harmful microbes in plastic

A Science book by Djamel Drider,Sylvie Rebuffat, with totalpages 451, file format PDF ePub, language English, file download 1915 kb. The book will provide an overview of the advancement of fundamental knowledge and applications of antimicrobial peptides in biomedical, agricultural, veter

A Medical book by Pranav Kumar Prabhakar,Dr. Vijay Mishra, with totalpages 368, file format PDF ePub, language English, file download 1635 kb. "This book contains comprehensive and up-to-date reviews of multidrug resistance mechanisms. The book intends to provide a state-of-the-art collection of r

A Technology & Engineering book by Alexandru Mihai Grumezescu, with totalpages 574, file format PDF ePub, language English, file download 1656 kb. Antimicrobial Nanoarchitectonics: From Synthesis to Applications brings together recent research in antimicrobial nanoparticles, specifically in the sustai

A Technology & Engineering book by Karina Yew-Hoong Gin,Charmaine Ng, with totalpages 188, file format PDF ePub, language English, file download 827 kb. This Special Issue on Antimicrobial Resistance in Environmental Waters features 11 articles on the monitoring and surveillance of antimicrobial resistance

A book by Mirian A. F. Hayashi,Fernando César Bizerra,Pedro Ismael Da Silva Junior, with totalpages N.A, file format PDF ePub, language English, file download 619 kb. Nature is a generous source of compounds with the potential to treat diseases, including infectious diseases, which is of utmost importance for modern medi

A Medical book by Sadhana Sagar,Shilpa Kaistha,Amar Jyoti Das,Rajesh Kumar, with totalpages 179, file format PDF ePub, language English, file download 1289 kb. This book summarizes the emerging trends in the field of antibiotic resistance of various gram-negative and gram-positive bacterial species. The ability of

A Medical book by Douglas Mayers, with totalpages 678, file format PDF ePub, language English, file download 601 kb. This ? rst edition of Antimicrobial Drug Resistance grew out of a desire by the editors and authors to have a comprehensive resource of information on anti